Protein Info for Psest_2951 in Pseudomonas stutzeri RCH2

Annotation: C-terminal peptidase (prc)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 694 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF17804: TSP_NTD" amino acids 48 to 235 (188 residues), 231.2 bits, see alignment E=2.5e-72 TIGR00225: C-terminal processing peptidase" amino acids 206 to 561 (356 residues), 314.4 bits, see alignment E=4.3e-98 PF00595: PDZ" amino acids 244 to 322 (79 residues), 35.1 bits, see alignment E=2.8e-12 PF03572: Peptidase_S41" amino acids 366 to 539 (174 residues), 169.1 bits, see alignment E=1.3e-53 PF11818: DUF3340" amino acids 544 to 685 (142 residues), 134.8 bits, see alignment E=5.9e-43

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 95% identity to psa:PST_1414)

Predicted SEED Role

"Periplasmic protease"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GQ56 at UniProt or InterPro

Protein Sequence (694 amino acids)

>Psest_2951 C-terminal peptidase (prc) (Pseudomonas stutzeri RCH2)
MKRTLTCTVLAVLFGLHASLAMAKAVSTPESWDYLQPDRDQVIASLNVVELLKRHHYNKP
PLNDARSAKIFDSYIQMLDPSRSYFLASDLEEFGKWRNQFDDFLKGGNLEPGFAIYKRHL
ERLQNRLNYALGLLDKGVGSFDFTKDEELLIDREKAAWAKNMAELDDLWRKRVKDEVLRL
KLAGKEPKAIEELLTKRYKNQLARLNQTRGEDVFQTYINAFAQSYDPHTQYLSPDNAENF
DINMSLSLEGIGAVLQSDNEHVKIVRLVPAGPAEKSKQLAPADKIVGVGQANDEMVDVIG
WRLDEVVKLIRGPKGSVVRLEVIPASNAPNDQSSKVVAITREAVKLEEQAAKKSVLNLEH
QGQSFKLGVIEIPAFYLDFKALRAGDQNYKSTTRDVKKLLSELEAEKVDGVVIDLRNNGG
GSLQEATELTGLFIDQGPTVLVRNSDGRVDVLADEQTGAYYKGPLAVLVNRLSASASEIF
AGAMQDYHRALILGGQTFGKGTVQTIQPLNHGELKLTLAKFYRVSGQSTQHQGVIPDITY
PADVDTKEIGESALPEALPWDSIRAAINPDMNPFKPFLAELKARHEARTGENPDFVFTRD
RLALAQELMHDTTVSLNEDKRRAQQADIEKRQLALENALRLAKGEQPLAKLEKEDETTPH
KETDKPKPEDDAYLSESGRILLDYLGLSSAMAKH