Protein Info for HP15_2839 in Marinobacter adhaerens HP15

Annotation: protein containing transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF00440: TetR_N" amino acids 27 to 73 (47 residues), 57.7 bits, see alignment 8e-20 PF17929: TetR_C_34" amino acids 97 to 207 (111 residues), 74.7 bits, see alignment E=7.1e-25

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PM91 at UniProt or InterPro

Protein Sequence (215 amino acids)

>HP15_2839 protein containing transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal domain (Marinobacter adhaerens HP15)
MVLKHRLCGGKQRARTESDKALREQQILDAAERLFLEHRFHGLTLADVARETGLTKAALY
RYFRSKELLFIAVYRRAMSGWVSDVEAVGPDGFPNQFVDRILAHPVFCGLTAILHIALET
GLSEEEAREFKLFLLSQSRRITAVIGKATNREEAACLRYLLQCQQALIGCWHMSHPPEPA
RKAMQLEPLTVFQLEFSDTLEHHLSILTKAFMQDE