Protein Info for Psest_2933 in Pseudomonas stutzeri RCH2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 914 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 186 to 204 (19 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 277 to 296 (20 residues), see Phobius details amino acids 302 to 324 (23 residues), see Phobius details amino acids 331 to 354 (24 residues), see Phobius details amino acids 360 to 382 (23 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 38 to 169 (132 residues), 122.4 bits, see alignment E=3.4e-39 PF07695: 7TMR-DISM_7TM" amino acids 184 to 384 (201 residues), 111.5 bits, see alignment E=1.4e-35 PF00512: HisKA" amino acids 408 to 473 (66 residues), 75.6 bits, see alignment 6.4e-25 PF02518: HATPase_c" amino acids 520 to 635 (116 residues), 105.7 bits, see alignment E=4.6e-34 PF00072: Response_reg" amino acids 789 to 904 (116 residues), 85.4 bits, see alignment E=7.7e-28

Best Hits

KEGG orthology group: None (inferred from 89% identity to psa:PST_1437)

Predicted SEED Role

"Sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GN65 at UniProt or InterPro

Protein Sequence (914 amino acids)

>Psest_2933 Signal transduction histidine kinase (Pseudomonas stutzeri RCH2)
MLPRACLALLLCCLSLQVWAFTPVVVDSIDSRQSLGGGTRYLEDPDGQLSVDDVMALSSE
RFRPVTGGHVNEGKNGSTWWLRADLKNRLGNPVGGFIEINYPLLDHIELFLQYPDGNISR
QLTGDIYPFAQRPVKVSNFWFPVELPPGDTTLLLRIKTTSTLYVPLYFSTYNASAAEEQE
LSGLSGAFYGVLFAMFCYNLFLFASLREPAYFWYLVYTLNVGLFALSFDGLLVKWLADDG
GLVALGIYALMFSHCLIAIQFSRHFLHTRELFPRLDLLLRCTLLAALGSMISGLVLDVQS
WSILASVTVIVVSAGLLLAGAFVWRRGVRYGVYYTLAWGVLLASFILVTAGSLGIELFGL
YGAGVVKASVAFELITLSIGLADRINLLKEEGYRSREAAERAASENEAKSRFLAKMSHEI
RTPLNGVLGMLQLLRETPLDRSQQFYLDTISSSGNSLMAVINDILDYARIGSGKLSLEDI
DFDLEILISETIRLFTAQSLEKQLSLHVGLEPGVPRRIRGDPTRLKQILMNLLSNALKFT
EHGHVLLEVSCRQTPDGGPRLVFCVSDSGIGMRQEVLAQLFESFSQGDSSTTRRYGGSGL
GLAISKELVEMMNGHIEVQSAPGRGSRFCFEIPLRTATDVEDPLTQLLAGRPALLASQDA
QGLEALSHLLRRWGMRTERCLTPDRLPDYLADFTAPPLLVLLAPWPGSPSQWLERLRPYL
EANQRMLMLYSPIHEPPPLTPDLRLISLALPLQSAPLREALQALYEREPAQSAETDKASI
APLQSEPCILVAEDNPVNQMVVRGLLKKRGYAVQLADNGRQAVDLYRRDPDAVQLILMDC
EMPELDGFEASRQIRKLEADQQLQAVPIIAVTAHVLAEHRQRGLESGMDEFIGKPLESRQ
LYACLDSYLQSGAS