Protein Info for PGA1_c28990 in Phaeobacter inhibens DSM 17395

Annotation: putative NADPH-dependent FMN reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 PF03358: FMN_red" amino acids 4 to 146 (143 residues), 133.6 bits, see alignment E=4.4e-43 PF02525: Flavodoxin_2" amino acids 5 to 112 (108 residues), 33.4 bits, see alignment E=3.9e-12

Best Hits

Swiss-Prot: 43% identical to FMNRE_PSEAE: NAD(P)H-dependent FMN reductase PA1204 (PA1204) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 72% identity to sil:SPO3573)

Predicted SEED Role

"NADPH-dependent FMN reductase domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DTZ7 at UniProt or InterPro

Protein Sequence (180 amino acids)

>PGA1_c28990 putative NADPH-dependent FMN reductase (Phaeobacter inhibens DSM 17395)
MSDPKILTISGSLRAGATNRKLLAEATRLFGPAEVTEADLNLPLYDGDDEQASGIPESVQ
RLADQIGAADAVIISTPEYNGAPSGVLKNALDWVSRTSNKPWQDKPVAIMSAAAGRAGGE
KSQMLLRTFLVPFQPRVLTAPQVHLAASHSEFDEGGRLLSELYTETLEALMTALRAEIAR