Protein Info for Psest_2894 in Pseudomonas stutzeri RCH2

Annotation: addiction module antidote protein, HigA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 126 TIGR02607: addiction module antidote protein, HigA family" amino acids 3 to 83 (81 residues), 103 bits, see alignment E=3e-34 PF01381: HTH_3" amino acids 17 to 66 (50 residues), 47.4 bits, see alignment E=1.6e-16 PF13560: HTH_31" amino acids 22 to 67 (46 residues), 34.3 bits, see alignment E=2.4e-12

Best Hits

Predicted SEED Role

"HigA protein (antitoxin to HigB)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKW0 at UniProt or InterPro

Protein Sequence (126 amino acids)

>Psest_2894 addiction module antidote protein, HigA family (Pseudomonas stutzeri RCH2)
MSMHNPPHPGEFITNIYLEPNGISGRELAEKLGVAPSTLSRVLNGTSRVTPEMALRLSVA
LGRSPESWLAMQDAYDLRVARQHVGKQAMLELADDAYLAEVVRARCDEPTVRLDIDSLIA
QAERTN