Protein Info for Psest_2890 in Pseudomonas stutzeri RCH2

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 281 to 299 (19 residues), see Phobius details PF02743: dCache_1" amino acids 35 to 263 (229 residues), 59.4 bits, see alignment E=7.5e-20 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 357 to 513 (157 residues), 137.4 bits, see alignment E=1.9e-44 PF00990: GGDEF" amino acids 362 to 510 (149 residues), 138.1 bits, see alignment E=4.9e-44 PF17853: GGDEF_2" amino acids 385 to 500 (116 residues), 24.7 bits, see alignment E=4.9e-09

Best Hits

KEGG orthology group: None (inferred from 85% identity to psa:PST_1497)

Predicted SEED Role

"diguanylate cyclase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GPZ9 at UniProt or InterPro

Protein Sequence (516 amino acids)

>Psest_2890 diguanylate cyclase (GGDEF) domain (Pseudomonas stutzeri RCH2)
MSRLDLQKLTLLLALVAGLLTFGNSFFAGYSSQRDQLFEQTLEANRSYARKLADTTDQFF
LNSRRELAYAAQTLSTRFDDPAARDNETERLKLKSDQFSRAIIVSAAGEIVSTSPESTDL
LGLKVNSIGANRALKERIPLTSDPYAATDGTYLIAVTHPIFAADGRYLGFISASLFLRER
NALHGLLGVHYYRDGSYLYVVDTQGRLIFHEDGKRVGQNVSSNPVVQQVLSGREGSQRVI
NTLGVDMLAGFAPMQSTGWGIVAQRPTAAITAKLEQLARTTLLNAVPFTLISLAVFWWLS
RLISRPIRALADTAEHWGAPEAASRISKVNSWYFEVSRLKVAMLAGVSLLQQKMGALEAA
SMTDPLTGLRNRRGLELALKQFDLLDQRYAAVTLDIDHFKQVNDQHGHDVGDAVLRFLAE
IMKECSRPTDVLCRMGGEEFLMLLPETGASGASIAAERLLARLRQTPSPTGTPITASIGI
ACSDRYPSPDATFKAADEALYQAKRAGRDRVVFASS