Protein Info for PGA1_c28750 in Phaeobacter inhibens DSM 17395
Annotation: aminotransferase class-III
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 46% identical to YGD3_SCHPO: Uncharacterized aminotransferase C1771.03c (SPBC1773.03c) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)
KEGG orthology group: K00837, [EC: 2.6.1.-] (inferred from 84% identity to sit:TM1040_0161)Predicted SEED Role
"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)
MetaCyc Pathways
- biotin biosynthesis I (13/15 steps found)
- biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)
KEGG Metabolic Maps
- Aminophosphonate metabolism
- Arginine and proline metabolism
- Biotin metabolism
- Caprolactam degradation
- Lysine biosynthesis
- Lysine degradation
- Methionine metabolism
- Nucleotide sugars metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.-, 2.6.1.62
Use Curated BLAST to search for 2.6.1.- or 2.6.1.62
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7F007 at UniProt or InterPro
Protein Sequence (440 amino acids)
>PGA1_c28750 aminotransferase class-III (Phaeobacter inhibens DSM 17395) MSHVFPRHTKADLPTAVAGDGCYLIDANGKRYLDGSGGAAVSCLGHSDAEVIAAVQEQVG KLAFAHTGFLTSEPAEALADLLISQAPGDLHRVYFVSGGSEATEAAIKLARQYHLERGDT TRRHVIARRQSYHGNTLGALAAGGNAWRRQQFAPLLIDISHIAPCYEYVDRGDGESRYDY GQRVANELEAEILRLGPETVMAFMAEPVVGATSGAVPAVEGYFKRIREICDQYGVLLILD EVMCGMGRTGHLFACEADGVAPDILCIAKGLGAGYQPIGAMLCSRQIYDAIEGGSGFFQH GHTYIGHPVATAAGLAVVRALLDRGLVQRSAEMGETLHAALVARFGQHPHVGDLRGRGLF RGIELVADRESKTPFDPGLGIAGKLKKAAFEAGLICYPMAGTRDGRNGDHILLAPPFILS EDQIGEITDKLEVALDQVLP