Protein Info for PGA1_c28680 in Phaeobacter inhibens DSM 17395

Annotation: putative bacteriophytochrome

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 858 PF08446: PAS_2" amino acids 15 to 121 (107 residues), 65.2 bits, see alignment E=2.2e-21 PF01590: GAF" amino acids 146 to 306 (161 residues), 52.1 bits, see alignment E=2.5e-17 PF00360: PHY" amino acids 326 to 503 (178 residues), 166.9 bits, see alignment E=7.9e-53 PF07536: HWE_HK" amino acids 525 to 607 (83 residues), 74 bits, see alignment E=3.3e-24 PF00072: Response_reg" amino acids 741 to 843 (103 residues), 33.2 bits, see alignment E=1.3e-11

Best Hits

KEGG orthology group: None (inferred from 49% identity to npp:PP1Y_AT9272)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-)" in subsystem Oxidative stress or Oxygen and light sensor PpaA-PpsR (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2C9 at UniProt or InterPro

Protein Sequence (858 amino acids)

>PGA1_c28680 putative bacteriophytochrome (Phaeobacter inhibens DSM 17395)
MALEQTVSTTTLTNCDREPIHQLGRVQSYGALIAVSTDWLVQHASDNLLEILGIEAQAAV
GHSLGDLIAEDAFTRIRRNLSALEAPDSNLRFFNIPLKDRSQAFDVSIHQSGRHLVIEFE
PKFERSDRDVMSEIYPHFSQLRRDEDISRLAQGAARGLQALSGFDSVMVYQFQPDHSGQV
IAEIRSDRTKKYEGMFFPASDIPVQARALYKRSLLRLIADVDDEGAAISPAFKIDGAPLD
LSLAVTRAVSPIHLEYLRNMGVRASMSVSIMKDGELWGLFACHHKRPRYIDYERRTAIEM
FAHVFSYELSQFETTQRSREEKSMSRLQTQLMAMLADGRTFKESLISVSEDIQDVIPHDG
LVLYSDGEFHATGTTPTAEETRSLARMLDLTIGATAFSTNQLESLHEPARDYIDRCAGIL
AIPISKRPRDYLILCRRNISQTVEWAGDPTKPMEVGPNGVRLTPRKSFEAWQETVEWRSA
PWADNSLHSANMLRTVLLEIFLKVTEANNAERARAQEQQQLLISELNHRVRNILNLMRGL
VTQTKGTARTLTEFTENLDGRIHSLARAHDQLTGEQWEPASLRALITCELEAYTTGRDDE
VVLTGPDALVTPVAFTTLALVLHELTTNSVKHGALSNGVGRVEIVLEEEDSGALLISWIE
RGGPPVTPPARRGFGSTIVENSIPHELKGDASVQYKTTGLEARFRIPTRYLDKIKHNESN
SIPDAPLSEAKEAPKLGGKALVVEDSFIIAMDLTAMLEDMGFFEVASASSVGKALDALAE
GGFEYAVLDVNLGSEQSVPVAEELARRGIPFVLTTGYGEVQDIVDIYPPCPIVQKPVSES
ALAAALLRAGERPATETP