Protein Info for HP15_2721 in Marinobacter adhaerens HP15

Annotation: ribosome-associated GTPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 TIGR00157: ribosome small subunit-dependent GTPase A" amino acids 67 to 313 (247 residues), 163.2 bits, see alignment E=4e-52 PF03193: RsgA_GTPase" amino acids 83 to 257 (175 residues), 162.5 bits, see alignment E=1.4e-51 PF00005: ABC_tran" amino acids 183 to 234 (52 residues), 27.6 bits, see alignment 6.4e-10 PF01926: MMR_HSR1" amino acids 192 to 273 (82 residues), 29.3 bits, see alignment E=1.3e-10

Best Hits

Swiss-Prot: 50% identical to RSGA2_VIBPA: Small ribosomal subunit biogenesis GTPase RsgA 2 (rsgA2) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

KEGG orthology group: K06949, ribosome biogenesis GTPase [EC: 3.6.1.-] (inferred from 67% identity to ttu:TERTU_2565)

Predicted SEED Role

"Probable GTPase related to EngC" in subsystem Universal GTPases

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKK9 at UniProt or InterPro

Protein Sequence (349 amino acids)

>HP15_2721 ribosome-associated GTPase (Marinobacter adhaerens HP15)
MSDLLESLGLVPFFIQQLPDLGLLQHRLGRVTSVQRSNYTVFTGSGEGRVEIASGLRQSS
ALDRPTVGDWVILDESLSRIEQVLERKTLFKRIGAGTNHEIQPIAANIDVLFIVSSCNEE
FKESRLERYLTLCAEAGAMPVIVLTKADLVDDVDDYVRRARNTQAGIPVETANTLDASTL
DGVRSWIDKHSTVALVGSSGVGKSTLVNTLAEQMLTATNDIREDDKKGRHTTTHRELHIL
PSGGLLVDVPGMRELRVADIDQSIGAVFEDIAKMAEECRFADCQHETEPGCAVLQAIEEN
KLDPRRLANYKKLQRENNLATATLAEKRAQGRAFAKAVKSGIDIKRKHR