Protein Info for HP15_2716 in Marinobacter adhaerens HP15

Annotation: lemA family domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details amino acids 231 to 251 (21 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 532 to 552 (21 residues), see Phobius details amino acids 562 to 581 (20 residues), see Phobius details PF12483: GIDE" amino acids 419 to 488 (70 residues), 31.7 bits, see alignment E=1e-11 PF04011: LemA" amino acids 595 to 731 (137 residues), 99.3 bits, see alignment E=2e-32

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKK4 at UniProt or InterPro

Protein Sequence (733 amino acids)

>HP15_2716 lemA family domain protein (Marinobacter adhaerens HP15)
MRRFNIASIPGRIITAIIAVACLAGSYYAMTTGLGKLTEARQLERLPDTPVGALTTGPYV
IAGEITDQLGTLETPYSKTEAVYYRYKLEEEYRDSDGDLRIRTLDSGARGRNFLLRDQTG
SVTVAAGGNPDAAEWILDRTYRQQSGRRIYSEWALVPGHTARVIGQYSSESTSLNFAGLE
DFSLPAMVSRNTLAADSGDRFFEAAIRISIATGLLALGIALILPLIRIHRFWVYVLVMTF
AVSGTLSVLGINKLRQEWSAIANLYEARYQKIEETSARSLVLADVAALQQLIRQSTSGWL
DRWMFRSVVQNRLPVPELDEQTASIARSIVASQPVGRYQHAWTSRGLAVASIIAALLLLW
LSIRTVKFKRLIEAVPTSSTRGLSFGLSELKAMVDVDDEHPPLRDPLKNEKCVAFDYKVE
EKRGSGKNEKWRVIEHREERAPFWLEDSEGKVLVQPDGAKIEYPQYHSERQGDRRYTVRF
LDTFVNVYCLGFAGLDRDQPDRLTIQKDEASPFLISGNEEEDIVLDRGARGFAGIALTLG
LFLFSTTALFAADGGFSPDNLILSALTVPIILLIYTGILHYNDIVFLKNRVDRAAANIDT
ILQQRHELWPNLEKVVKASLAHEKQLLKAIAQLRSADPVEMSSNGQADKLMQFEKKVTNA
LQARIEGYPDLKNNEVIQKFMSIMAETENYLSLLRNSFTESAMIYNTRIQSFPDVILAKL
FRFREAPQFSSET