Protein Info for HP15_2629 in Marinobacter adhaerens HP15

Annotation: PpiC-type peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13145: Rotamase_2
  • amino acids 9 to 93 (85 residues), 32.8 bits, E=1.7e-11
• PF00639: Rotamase
  • amino acids 14 to 91 (78 residues), 78.1 bits, E=1.3e-25
• PF13616: Rotamase_3
  • amino acids 15 to 93 (79 residues), 81.5 bits, E=1.1e-26

Best Hits

Swiss-Prot: 52% identical to PPIC_ECOL6: Peptidyl-prolyl cis-trans isomerase C (ppiC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03769, peptidyl-prolyl cis-trans isomerase C [EC: 5.2.1.8] (inferred from 98% identity to maq:Maqu_2883)

MetaCyc: 52% identical to peptidyl-prolyl cis-trans isomerase C (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

See E4PJM9 at UniProt or InterPro

Protein Sequence (94 amino acids)

>HP15_2629 PpiC-type peptidyl-prolyl cis-trans isomerase (Marinobacter adhaerens HP15)
MIMAQATARHILVDSEAKCEELKKAIEGGQDFAEVAKQHSSCPSGRNGGDLGSFGPGQMV
PEFDKAVFNGELNTVIGPVKTQFGYHLLEVTSRS