Protein Info for HP15_267 in Marinobacter adhaerens HP15

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 PF12418: AcylCoA_DH_N" amino acids 2 to 33 (32 residues), 31.8 bits, see alignment (E = 2.9e-11) PF02771: Acyl-CoA_dh_N" amino acids 42 to 158 (117 residues), 49.4 bits, see alignment E=1.4e-16 PF02770: Acyl-CoA_dh_M" amino acids 163 to 267 (105 residues), 54.5 bits, see alignment E=2.7e-18 PF00441: Acyl-CoA_dh_1" amino acids 278 to 447 (170 residues), 71.2 bits, see alignment E=2.7e-23 PF12806: Acyl-CoA_dh_C" amino acids 476 to 584 (109 residues), 113.4 bits, see alignment E=2e-36

Best Hits

KEGG orthology group: None (inferred from 91% identity to maq:Maqu_0515)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKY9 at UniProt or InterPro

Protein Sequence (591 amino acids)

>HP15_267 acyl-CoA dehydrogenase family protein (Marinobacter adhaerens HP15)
MQYQAPANDLRFLLFDVLGADRLHELEKYADATPDLISAVIDEAGKLAAEVIQPTNQAGD
REGCTYDPETHSVKTPECFKDAYKKFVQGGWTALDAPLEYGGQGLPHTLKFVVDEMVCST
NLSLGMYPGLTHGAISALYAHGSEELKKTYLEKLISGEWTGTMCLTEPQCGTDLGLIRTR
ATPNDDGSYALEGTKIWITGGEHDLVDNIVHLVLAKLPGAPDTTKGISLFVVPKFLPESG
ERNPAFCGGLEHKMGIKGSATCVMNFEGAKGWLVGEPNDGMRAMFTMMNEARLMVGMQGL
GLAEMAYQESLGFARERLQSRSLSGPKNPDGPADPIIVHPDVRRMLMRQKVLNEGMRALA
LFAGHQLDLSVAHPDETVRESADDLVQLLTPVVKSFLTDEGFNNANTGLQVLGGSGFTTD
WPLEQLVRDGRIARIYEGTNGIQAMDLVGRKLSLKGGQLVRTLFGTLSGYLKDNPEAPHR
EELKNAMKALETATMWLASNAPKDPEQAGAAATPYLRLMALTVIGYLWSRMANVANEQLA
AGEGNKPLLESKVVSARFYFEKLLPEVDWLLGDIQSGKDSLMAFSDDHWAA