Protein Info for Psest_2727 in Pseudomonas stutzeri RCH2

Annotation: Small-conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 91 to 112 (22 residues), see Phobius details amino acids 126 to 149 (24 residues), see Phobius details amino acids 155 to 177 (23 residues), see Phobius details PF21088: MS_channel_1st" amino acids 135 to 174 (40 residues), 34.4 bits, see alignment 2.6e-12 PF00924: MS_channel_2nd" amino acids 175 to 242 (68 residues), 69.1 bits, see alignment E=4.4e-23 PF21082: MS_channel_3rd" amino acids 248 to 333 (86 residues), 38.9 bits, see alignment E=1.5e-13

Best Hits

KEGG orthology group: None (inferred from 94% identity to psa:PST_1641)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GPJ0 at UniProt or InterPro

Protein Sequence (380 amino acids)

>Psest_2727 Small-conductance mechanosensitive channel (Pseudomonas stutzeri RCH2)
MNWDALLNETFWINLAIVLGITIVSFLVLRTILGIVTRRLSKLASGAKTKFLGIAAELLS
RTSNLLILAFSLLIALKTVELSPRWESTMSHGWFIALAFQFALWMDTGVRLWMESLTRDG
KARNPVTTTIIGIMIRIVVWTMMLLSILANLGVDITAMVASLGVGGIAIALAVQTLLSDI
FASLSIGVDKPFEIGDFVVFGEVAGNIEHIGLKTTRIRALSGEQVVIANADLLRQIVHNY
KRMNTRRIVFKFGITYNTPTDKVKEVAALVKRIIDGIEVAKFDRAHFLGFDDSQLTFEVV
YIMQVSDYNRYMDTQQEINLALLEGMREMGVQFAFPTRSVEFIGGSLPEISVAGVPQEKP
AANQNGVDAERQSRDAQPRA