Protein Info for HP15_2609 in Marinobacter adhaerens HP15

Annotation: acyl-CoA transferase/carnitine dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 5 to 374 (370 residues), 393.6 bits, E=4.6e-122

Best Hits

KEGG orthology group: None (inferred from 60% identity to rfr:Rfer_4198)

MetaCyc: 38% identical to succinyl-CoA-glutarate CoA-transferase (Pseudomonas putida)
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

• L-lysine degradation X (5/6 steps found)
• L-lysine degradation IV (3/5 steps found)
• oxalate degradation II (1/3 steps found)
• superpathway of L-lysine degradation (12/43 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.3.13 or 2.8.3.16

Sequence Analysis Tools

See E4PJK9 at UniProt or InterPro

Protein Sequence (398 amino acids)

>HP15_2609 acyl-CoA transferase/carnitine dehydratase (Marinobacter adhaerens HP15)
MTKPLEGVRIIDLTHMLSGPYAGMLLADMGAESIKVEPLKGEGTRSLLAKDPRNSYNGHG
AYFITLNRNKKSVCIDLKSEAGLQTFYDLVKDADIVLDNFSAGVPAKLKIDHEHLSRVNP
RIITCSVTGFGQAGPNFKRPAFDQVVQGIGGGMSITGHDAEHPARAGIPIGDLGGGMFAV
MGVLAALHSRAVNGYGQHVDISMLDCQISMLNYMATMYFLSGDNPSPIGNGHFVHVPYDA
FRTSNGFVIIAVIFDSFWDNLVELLGIDELRDPAYKTQPGRFADKHKINGILTDLLKTNT
TEHWVELLSSARIPCAPVNKFSDALSDPQVLFRNMVVDIPQFDGGTVKAPGNPIKLSVDS
SDSYTAPPLLGQHTEDVLKSLGYSDERIAELKAMQAIG