Protein Info for Psest_2710 in Pseudomonas stutzeri RCH2

Annotation: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 215 to 228 (14 residues), see Phobius details PF00072: Response_reg" amino acids 9 to 113 (105 residues), 104.6 bits, see alignment E=3.4e-34 PF07228: SpoIIE" amino acids 201 to 391 (191 residues), 106.9 bits, see alignment E=1.3e-34

Best Hits

KEGG orthology group: None (inferred from 97% identity to psa:PST_1658)

Predicted SEED Role

"Serine phosphatase RsbU, regulator of sigma subunit" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKE4 at UniProt or InterPro

Protein Sequence (394 amino acids)

>Psest_2710 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains (Pseudomonas stutzeri RCH2)
MLKPSATLLIIDDDDVVRASLAAYLDDSGFRVLQAANGPQGMDLFDSEQPDLVICDLRMP
QMDGLELIRQISERQIDLPVIVVSGAGVMSDAVEALRLGAADYLIKPLEDLAMLEHSVRR
ALDRSRLRLENRRYREQLETANRDLQASLHLLQEDQDAGRQVQMNMLPVTPWSVDGFDFA
HQIIPSLYLSGDFVDYFRVDERRIGFYLADVSGHGASSAFVTVLLKFMTTRLLYESRRGG
MLREFKPSEVLDHINRGLINCKLGKHVTMLGGVIDQEHDVLHYSIGGHLPMPVLYTGDSA
HYLEGRGLPVGLFVEATYQNFELKLPESFSLTLLSDGILDLLPGETLKEKESALPGLITQ
AGGTLDGLRRVFGLAELADMPDDIALLVLSRNLA