Protein Info for PGA1_c26940 in Phaeobacter inhibens DSM 17395

Annotation: cytosine deaminase CodA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 PF07969: Amidohydro_3" amino acids 40 to 400 (361 residues), 198.4 bits, see alignment E=3.4e-62 PF01979: Amidohydro_1" amino acids 49 to 399 (351 residues), 56.1 bits, see alignment E=3.7e-19

Best Hits

KEGG orthology group: K01485, cytosine deaminase [EC: 3.5.4.1] (inferred from 77% identity to pgv:SL003B_2461)

MetaCyc: 44% identical to cytosine deaminase monomer (Klebsiella pneumoniae)
Cytosine deaminase. [EC: 3.5.4.1]; 3.5.4.1 [EC: 3.5.4.1]; 3.5.4.1 [EC: 3.5.4.1]

Predicted SEED Role

"Cytosine deaminase (EC 3.5.4.1)" (EC 3.5.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EQ24 at UniProt or InterPro

Protein Sequence (427 amino acids)

>PGA1_c26940 cytosine deaminase CodA (Phaeobacter inhibens DSM 17395)
MMLDLLIKGGTLPDGSVADIGITGDTITEVAPSIDATAGETIEASGDLVAPPFVDAHFHM
DATLSYGLPRVNASGTLLEGISLWGELREEASIEDMVNRALTYCDWAASMGLLAIRTHVD
TTPDHLRGVTAMLEVREAVKEYIDLQLVAFPQDGLYRTENGRENLIRALDMGVDVVGGIP
HFERSMQDGAESLRDLCRIAADRGLQVDIHCDETDDPLSRHIETLAQETLRHGLQGRVAG
SHLTSMHSMDNYYVSKLLPLIAEAGIAAIPNPLINIVLQGRHDSFPKRRGLTRVKELLAH
GVTVGWGQDCVLDPWYSLGTGDMLDVAFMGMHVAQMTHPDEMAQCFTMVTESNAAIMGLD
GYGLKKGDRASLVVLDAATPTEALRLRPARLAVVAKGKVVSRSARGDADISIPGRPAQVR
RRHQMPG