Protein Info for PGA1_c26580 in Phaeobacter inhibens DSM 17395

Annotation: putative tryptophan halogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 PF04820: Trp_halogenase" amino acids 7 to 469 (463 residues), 433.7 bits, see alignment E=4.4e-134

Best Hits

Predicted SEED Role

"Tryptophan halogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DTD4 at UniProt or InterPro

Protein Sequence (561 amino acids)

>PGA1_c26580 putative tryptophan halogenase (Phaeobacter inhibens DSM 17395)
MNNRLRKITIVGGGTAGWMTALILETELSRTSAPKDRPKICLIESPNIATVGVGEATVPR
MPKTLRQAGISERAFFRETNASFKLGVKFCNWNKDAKGNRIDYVNPFAHGQLLDGLEPAE
YFLRFGNGDRDYTQSIAPHDDLGRLCKGARPLGQPEFEQRFGYAYHLDAVKFAGMLTKVC
TKHGVEHIQDEVTSVELDEQGNVSHLMLEQRGRHDIEMVIDCTGFRGLIINQALGEPFMD
YSDYLPNDRAMALQIDHPDPEKIESLTRSTALGAGWTWRVPLYNRVGTGYVFSSAHRTDD
QAADEYLEWLGDSGKGATPRIIPMRIGRVRNAWVKNCVAIGLAGGFIEPLESTAIHMIDH
AVRWLTEHMPTRDIAPSLRTRYNRQMDKLYDEVLEFICLHYRLGNRTDDQYWIDARTEMK
IPDRLAENLELWQHRLPMSHDIEFATLFDYRVYQTVLLGKQVYDTGYGPGIRDRLRPLKK
PIWFQWWKGAKADLAQILKAMPDHKTLLRDIRGELDQPGFGMAAAMKPTVPMPGAAPVPW
AIQNMPSFSEIESGQKDLQLF