Protein Info for PGA1_c26500 in Phaeobacter inhibens DSM 17395

Annotation: rod shape-determining protein MreB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR00904: cell shape determining protein, MreB/Mrl family" amino acids 11 to 340 (330 residues), 490.4 bits, see alignment E=1.3e-151 PF06723: MreB_Mbl" amino acids 13 to 340 (328 residues), 475.5 bits, see alignment E=1.7e-146 PF00022: Actin" amino acids 37 to 206 (170 residues), 34 bits, see alignment E=3.3e-12 PF00012: HSP70" amino acids 108 to 205 (98 residues), 36.2 bits, see alignment E=5.5e-13 PF14450: FtsA" amino acids 161 to 320 (160 residues), 40 bits, see alignment E=1.2e-13

Best Hits

Swiss-Prot: 66% identical to MREB_CAUVN: Cell shape-determining protein MreB (mreB) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03569, rod shape-determining protein MreB and related proteins (inferred from 97% identity to sit:TM1040_0473)

Predicted SEED Role

"Rod shape-determining protein MreB" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EPZ0 at UniProt or InterPro

Protein Sequence (348 amino acids)

>PGA1_c26500 rod shape-determining protein MreB (Phaeobacter inhibens DSM 17395)
MSIFGSLGGLFTSDMAIDLGTANTLVYVKGRGVILSEPSVVAYHVKDGVKKVLAVGEDAK
LMLGRTPGSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSKPKIIVCVPHGATPV
EKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITDPTGNMVVDIGGGTTEVAVLSLGDI
VYARSVRVGGDRMDEAIINYLRRQQNLLIGESTAERVKTSIGTARMPDDGRGQSMQIRGR
DLLNGVPKEIEVSQAQVAEALAEPVQQICEAVMTALETTPPDLAADIVDRGVMLTGGGAL
LGDLDLALREQTGLAVSIADESLNCVALGTGKALEYEKQLAHAIDYDS