Protein Info for Psest_2646 in Pseudomonas stutzeri RCH2

Annotation: SOS regulatory protein LexA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 202 PF01726: LexA_DNA_bind" amino acids 1 to 65 (65 residues), 103.4 bits, see alignment E=4.5e-34 TIGR00498: repressor LexA" amino acids 1 to 202 (202 residues), 254 bits, see alignment E=4.6e-80 PF00717: Peptidase_S24" amino acids 81 to 194 (114 residues), 120.9 bits, see alignment E=2.3e-39

Best Hits

Swiss-Prot: 90% identical to LEXA_PSEMY: LexA repressor (lexA) from Pseudomonas mendocina (strain ymp)

KEGG orthology group: K01356, repressor LexA [EC: 3.4.21.88] (inferred from 90% identity to pfs:PFLU1560)

Predicted SEED Role

"SOS-response repressor and protease LexA (EC 3.4.21.88)" in subsystem DNA repair, bacterial (EC 3.4.21.88)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMZ3 at UniProt or InterPro

Protein Sequence (202 amino acids)

>Psest_2646 SOS regulatory protein LexA (Pseudomonas stutzeri RCH2)
MIKLTPRQTEILAFIKRCLEDNGYPPTRAEIAHELGFKSPNAAEEHLKALARKGAIEMTP
GASRGIRIPDFEPAASENGLPIIGRVAAGAPILAQQHVEESCQISPAFFHPRADYLLRVH
GMSMKDVGIFDGDLLAVHTTREARNGQIVVARVGDEVTVKRFKRDGKKVWLLAENPEFAP
IEVDLEQQELVIEGLSVGVIRR