Protein Info for PGA1_c02690 in Phaeobacter inhibens DSM 17395

Annotation: Hemolysin-type calcium-binding repeat (2 copies).

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 969 PF00353: HemolysinCabind" amino acids 94 to 128 (35 residues), 32.8 bits, see alignment (E = 5.4e-12) amino acids 129 to 155 (27 residues), 16.8 bits, see alignment (E = 5.7e-07) amino acids 237 to 264 (28 residues), 20.2 bits, see alignment (E = 4.9e-08) amino acids 257 to 288 (32 residues), 28.2 bits, see alignment (E = 1.5e-10) amino acids 284 to 299 (16 residues), 10.5 bits, see alignment (E = 5e-05) amino acids 444 to 472 (29 residues), 25.6 bits, see alignment (E = 9.8e-10) amino acids 474 to 488 (15 residues), 8.5 bits, see alignment (E = 0.00022) amino acids 555 to 588 (34 residues), 27.7 bits, see alignment (E = 2.1e-10) amino acids 590 to 624 (35 residues), 21.4 bits, see alignment (E = 2e-08) PF13403: Hint_2" amino acids 726 to 865 (140 residues), 116.8 bits, see alignment E=1.1e-37

Best Hits

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1)" in subsystem Phosphate metabolism (EC 3.1.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ETJ8 at UniProt or InterPro

Protein Sequence (969 amino acids)

>PGA1_c02690 Hemolysin-type calcium-binding repeat (2 copies). (Phaeobacter inhibens DSM 17395)
MAVGYLVTLGDGTLDSGDGISANQSAFTSSDVIGTGSWTWSGQYQGDGQTYSNVTDTGTY
HYGSDGNVYFVPDTWYTTSGSASATTIPANSMSGTSGNDTISGDANDNVIYGGDGDDYLT
GSSGDDIIFGGEGSDNYDTDTGNDTFYGEGGDDWVAIYDNMDGESLYGGETGETLGDMLE
VYGDYAGVDVNVTFTGDGDGTVTFGGQTAYFWEFERFYLHSGDDTLDGSAATSAINVQTG
GGDNSVTGGMGDDTISTGAGADTVDGGAGADSIDAGSGDDVVTGSSGDTLLGGAGNDQIT
INAASGGSVAPSGATVVTDGGSASGDYDSNDFAWNPGSSSSSSISMGGTPGTTGSDDVYD
SITVLNTTDGAFLGVSQFDVGIDKVYLSEEPVSFTNTLASSGVSDFVVTYANGNTQSFRF
YNDGGAAISDPAQFFGTSVISGATLSGGEGDDTLTGGYGADSIDGGDGQDQIILQDGFGN
DTITGGEGGVDQDSLDLSQLSSGAVITMSGPEAGTVTVGSDTAQFSEIESITGTEKSDYI
DGSAQSGNLAYVNSGGGDDTILGGSGNDDLQGGAGNDRLEGRAGTDDLRGGTGDDYLDGG
TGGDYIDAGTGSDTVIGGTGDDTIQLTADADRDEVILEDGSGSDLIYNFDLGDSGDGTTV
DQLDVSGLTNLAGDPVKIGDIVVTDTNGDGTGDAIMTFPNGESITLVGVQSSQVDNGPEM
HAMGIPCFTAGTLIDTPTGPVRAEDLSPGDYVTTLGAGVQRVLWVGASFSTTARKQLPEA
LMPVRLSSDAFGSDEAPVVSPQHCILMKHRSSGRPLHLRAKHLAQMTDFASFACEMTQVT
YVHILLKTHDNLMSNGIPSETFYPGPMAVSTLRPADRLCLYKCLPQLILYRVEQAYGPRI
LPVLARREVRSLSDGGELVPWRGTDETPDLLNNDRLARALWQVDSSQERIYQPSSDSSSG
VLSSGLSLS