Protein Info for HP15_256 in Marinobacter adhaerens HP15

Annotation: serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 738 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01734: Patatin" amino acids 36 to 227 (192 residues), 121.2 bits, see alignment E=6.5e-39 PF07244: POTRA" amino acids 343 to 412 (70 residues), 28.4 bits, see alignment E=2.3e-10

Best Hits

KEGG orthology group: K07001, (no description) (inferred from 72% identity to maq:Maqu_0503)

Predicted SEED Role

"putative patatin-like phospholipase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKX8 at UniProt or InterPro

Protein Sequence (738 amino acids)

>HP15_256 serine protease (Marinobacter adhaerens HP15)
MSQCNPWGRNAPRLIAVIMILLAPLASAEERPKVGLVLSGGGAKGMAHVGVLRVLEEMRV
PVDLVVGTSAGSAVGALYASGMPVSDIEQRFIEMDWLSSFRDDPGRVYKPVRRKQDDWRF
PVVPGIGVRADGLRVGGGLIAGQNLGFILNELTHNAALVEDFDRLPIPFRAVATDLETGE
QVVIGDGNLSEAIRASMSIPGVYAPVERDGQLLVDGGVANNLPISVARDLGADIIIAVDI
TDSLMETDELRGAFSVVGQLTTIMTRRNTDQQLDLLAEDDVLIRPDLEGYTSADFYDAPV
LFELGASSAREHGVELRPLALSRKAWADWRDSVSAQDAGARIVSRIEIKDSRRLARDFLK
ERIRQRIGEPLDTARLEADLKRIYGLGYYEIVSYSTSSLPEGTVLTIRVQEKSWGPNYLS
FGLSYEDNFDGETRFNLASSLRMTELNALGGEWQTGVQLGTEPWVRSQWYQPLDYGYERF
LVLGGEYSRDTFSLFDAAGTRVTEVDVTFRKADLALGMEIGGNAEVRLIYARGYATVDEQ
IGQPVAPEGSVHQGGLAVQLVHDSLDDTFYPRDGGFAGLRGRFEREGLGSDREFDSVTGL
ALGTGSWKGLTLTGLVFGHAVTRGTPGIENAVRLGGFRRLSAYAPGEITGDNALMVSAYA
SQTFGGPLLPWFVGAGFEAGNAWPSLDEASWDSSVKSSSVFAGVDTFLGPVQVAAAYNNE
DNWTAYLNIGFSFTQLFY