Protein Info for Psest_2617 in Pseudomonas stutzeri RCH2

Annotation: Flp pilus assembly protein TadC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 140 to 161 (22 residues), see Phobius details amino acids 292 to 317 (26 residues), see Phobius details PF00482: T2SSF" amino acids 180 to 307 (128 residues), 77.2 bits, see alignment E=5.8e-26

Best Hits

KEGG orthology group: K12511, tight adherence protein C (inferred from 63% identity to pba:PSEBR_a4085)

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GK66 at UniProt or InterPro

Protein Sequence (322 amino acids)

>Psest_2617 Flp pilus assembly protein TadC (Pseudomonas stutzeri RCH2)
MDYLWSVFNGLMGDERWVRLLFLAAIGISAVIAALTLTLLVVGLQDPVHRRLVTLKRGMV
DQGVGEPPRGNLQLLLAQLGDRLVATDSEHASGTRALLLHAGYRSASAAQLYWSLRLLLP
LLLLAAAVVLLPLFSEVEFLTGLMLTAAAVIVGWMIPAIYVEKRKEARMNRLRAAFPDAL
DLLVVCVESGLALPQAIERVAEETSVSHAELAGELALVNAEIRAGVSSSDALQNLALRTG
LEDLQGLVSLLSQSIRFGTSVADTLRIYAEEFRDRRTQAAEEQAAKIGTKLVFPLILCLW
PSFFVVAIGPAIMALVNAFGSS