Protein Info for HP15_253 in Marinobacter adhaerens HP15

Annotation: extracellular solute-binding protein, family 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 902 transmembrane" amino acids 489 to 508 (20 residues), see Phobius details PF00497: SBP_bac_3" amino acids 262 to 477 (216 residues), 74.3 bits, see alignment E=1.2e-24 PF00512: HisKA" amino acids 552 to 617 (66 residues), 78.8 bits, see alignment 3.8e-26 PF02518: HATPase_c" amino acids 665 to 792 (128 residues), 105.3 bits, see alignment E=3.9e-34

Best Hits

Predicted SEED Role

"FIG00783944: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKX5 at UniProt or InterPro

Protein Sequence (902 amino acids)

>HP15_253 extracellular solute-binding protein, family 3 (Marinobacter adhaerens HP15)
MLGKEELTWLEGQDRFRIGLRSDQVPLVFDTGNGVLAGTYIDYLARLSDKLGVAMEPIVL
ETGQDSGPVRSELATDAVLTTRMPGMPVVPGKRFTDPLMSLTYGVFVSAGDAAIRTLADL
EGSRIAVIAGDPNQYPMLDPVEEFTPVPVSNVSEAVGQILSGQADAFLAPVPVVSDYLQS
AMVNGIGLSVLLDNSPVDVVLRVDTDRDLLYQVLNKAIAAIGHNEHRTIRQSWLQADQPS
LERSGLELSGSDMEWLKQHPDLKVAFRADWPPFEYTQDGRPTGLVPDLLTRLETELNVRF
TRTVAGSRMDAEEKLRSGEVDILPGLSRTPRTEEAFLFTRAYLTVPIALAIRDDGRFIGD
LRELRTERVGVVNRHAAHDYLLINHPNLDLYPMDTVEEGLLALSNGDLDVMVTHIPAVSY
TVARLGLSNLRITSITPYQYDLRLAVRKDNPELHRVLNKALGSLEASETESIYNRWIHLD
IEQETDYTVVRRVVLIAILVVLIFLYWNRKLSREVDERIRSENALRRSEDELRAAKLEAE
RLAREAEAASLAKSEFLANMSHEIRTPMNAVIGYSDLLSNSVTDPQQRNYLDAIRAGSRS
LLMLINDILDLSRIEAGKMRLDYSAVSVRRLLDDVRHIFDLRAREQGITLEVSVDSRMPG
AMMLDETRLRQVLFNLVGNAIKFTHDGGVTVRATAKPLKKRSAEAEQNPEAPERQYYKLI
VTVSDSGIGIPPDQVERIFDAFEQQEGQNTRRYGGTGLGLAISRKLARMMGGELEVESEQ
GSGSVFTVTLPRVEATVEQAEDEGVPKESDRLLAQTLSMQERGWLREQLAADFGDEWEAV
RESGDPEQMKDFARRVLAWGQRFRSRSVTRYGEKLLADVEAFNLDAVNSALEAFPKLLGR
EE