Protein Info for PGA1_c02650 in Phaeobacter inhibens DSM 17395

Annotation: Zn-dependent hydrolases, including glyoxylases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00753: Lactamase_B" amino acids 80 to 248 (169 residues), 63.3 bits, see alignment E=1.6e-21

Best Hits

KEGG orthology group: None (inferred from 56% identity to sil:SPO0788)

Predicted SEED Role

"Metallo-beta-lactamase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DX30 at UniProt or InterPro

Protein Sequence (305 amino acids)

>PGA1_c02650 Zn-dependent hydrolases, including glyoxylases (Phaeobacter inhibens DSM 17395)
MTVTRRRFVQGLGAGMALLPAGRVWAETRVSLGGAEVLSLSDGQMRLPPSFLYGDLDPAM
LAPVLAKHGMTPDDPLTPAINITLLRDADRIVLFDAGAGPGFQDGAGLLPDALAAAGISP
EDITHVVFTHCHPDHLWGVLDDFDDPLFANAKHLMGRQEWDYWFDPATVDTIGEDRASMA
VGARRRMEILADRITLFDDGAELLPGIAARATFGHSPGHMSFEIARGTDRIMILGDAVTN
AHVSFSEPSWEIASDQDPVTAARVRQQLLQQLAAEQLLVVGYHLPDGGMGYVEATGGGYR
FVPGI