Protein Info for PGA1_c25430 in Phaeobacter inhibens DSM 17395

Annotation: putative arylsulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 PF00884: Sulfatase" amino acids 3 to 398 (396 residues), 169.9 bits, see alignment E=1.3e-53 PF01663: Phosphodiest" amino acids 311 to 344 (34 residues), 25 bits, see alignment (E = 2.1e-09) PF16347: SGSH_C" amino acids 359 to 490 (132 residues), 33.1 bits, see alignment E=9.2e-12

Best Hits

Predicted SEED Role

"Choline-sulfatase (EC 3.1.6.6)" in subsystem Choline Transport or Choline and Betaine Uptake and Betaine Biosynthesis (EC 3.1.6.6)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.1.6.6

Use Curated BLAST to search for 3.1.6.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EPL5 at UniProt or InterPro

Protein Sequence (508 amino acids)

>PGA1_c25430 putative arylsulfatase (Phaeobacter inhibens DSM 17395)
MPPNVILIMTDQQRADSLGCTGNPVARTPHIDALAARGAVFRNHFTPHQICSPSRSTLFS
GLFARHHGLTRNGVALPEHLPLITHDLKDAGYRTHGAGKFHFQPILAGPEHEMPDSNAFW
ELPQSEGWAGPFYGFDKVDILIGESVSATEGGHYANWLRETAPDAAALYLPENALEPGPE
DLDEVWKSAIPSELHYNNWITDRACGFLEERDGEQPFFLFVSYPDPHHPFSPPAPWCDMY
DPQEVPAPALTADELAAMPSYILDGDREEAGKSYVDFLRNPGPPREQGFMQTTQRFSEAS
LRQAIAHTYGMVSMIDNCIGRLLAQLEAQGLAEDTLIIFTSDHGELLGDHGLIRKGPSPY
RPLLHVPLVIAGPGVAPGTREGVTSHLDLRATLQAHLGLESRRQDGQSFQALLTAADACG
RSHLYAEYHPRTRMETYNQTLLTEEWRVTIYPENPEWGEMFHLTEDPGEHVNLFFHPDYT
VQKQAFIEQMDREFPPAAQAGGPSLATY