Protein Info for Psest_2527 in Pseudomonas stutzeri RCH2

Annotation: cytochrome c oxidase, cbb3-type, subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 130 to 150 (21 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 205 to 226 (22 residues), see Phobius details amino acids 237 to 255 (19 residues), see Phobius details amino acids 270 to 295 (26 residues), see Phobius details amino acids 307 to 327 (21 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details amino acids 435 to 454 (20 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 9 to 472 (464 residues), 770.2 bits, see alignment E=4.3e-236 PF00115: COX1" amino acids 13 to 443 (431 residues), 384.1 bits, see alignment E=4.5e-119

Best Hits

Swiss-Prot: 87% identical to CCON1_PSEST: Cbb3-type cytochrome c oxidase subunit CcoN1 (ccoN1) from Pseudomonas stutzeri

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 99% identity to psa:PST_1840)

MetaCyc: 88% identical to cbb3-2 cytochrome c oxidase subunit N (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GP02 at UniProt or InterPro

Protein Sequence (475 amino acids)

>Psest_2527 cytochrome c oxidase, cbb3-type, subunit I (Pseudomonas stutzeri RCH2)
MSTAISETAYNYKVVRQFAIMTVVWGIIGMGLGVLIAAQLVWPSLNFDLPWTSFGRLRPL
HTNAVIFAFGGCALFATSYYVVQRTCQARLFSDGLAAFTFWGWQAVIVLAVITLPQGFTS
SKEYAELEWPIDILITLVWVSYIGVFFGTIMKRKAKHIYVGNWFFGAFILVTAMLHIVNN
LEIPVSWFKSYSIYSGATDAMVQWWYGHNAVGFFLTTGFLGMMYYFVPKQAERPVYSYRL
SIVHFWALITLYIWAGPHHLHYTALPDWAQSLGMVMSIILLAPSWGGMINGMMTLSGAWH
KLRTDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMITI
GSMYHLIPKVFGREQMHSIGLINAHFWLATIGTVLYIASMWVNGITQGLMWRAINEDGTL
TYSFVEALEASHPGFIVRALGGAFFLAGMLLMAYNTWRTVRVAKAAQYDAAAQIA