Protein Info for PGA1_c24990 in Phaeobacter inhibens DSM 17395

Annotation: riboflavin biosynthesis protein RibF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06574: FAD_syn
  • amino acids 13 to 165 (153 residues), 172.6 bits, E=5.6e-55
• TIGR00083: riboflavin biosynthesis protein RibF
  • amino acids 20 to 307 (288 residues), 238 bits, E=1.5e-74
• PF01687: Flavokinase
  • amino acids 182 to 307 (126 residues), 124.9 bits, E=2.3e-40

Best Hits

KEGG orthology group: K11753, riboflavin kinase / FMN adenylyltransferase [EC: 2.7.1.26 2.7.7.2] (inferred from 83% identity to sit:TM1040_2071)

Predicted SEED Role

"Riboflavin kinase (EC 2.7.1.26) / FMN adenylyltransferase (EC 2.7.7.2)" in subsystem Riboflavin, FMN and FAD metabolism (EC 2.7.1.26, EC 2.7.7.2)

MetaCyc Pathways

• adenosylcobalamin biosynthesis II (aerobic) (28/33 steps found)
• flavin biosynthesis I (bacteria and plants) (8/9 steps found)
• flavin salvage (2/2 steps found)
• flavin biosynthesis III (fungi) (7/9 steps found)
• 5,6-dimethylbenzimidazole biosynthesis I (aerobic) (2/3 steps found)
• flavin biosynthesis II (archaea) (5/10 steps found)
• roseoflavin biosynthesis (1/7 steps found)

KEGG Metabolic Maps

• Riboflavin metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.26 or 2.7.7.2

Sequence Analysis Tools

See I7EPG7 at UniProt or InterPro

Protein Sequence (310 amino acids)

>PGA1_c24990 riboflavin biosynthesis protein RibF (Phaeobacter inhibens DSM 17395)
MRIIRDFQFVDPKDRGAVAAIGNFDGVHRGHQSVIDLAREAEPQAPLGVMTFEPHPREFF
APDAKPFRLMSAEARASRLEKLGVERLYQLNFNAALSGLTPEAFARKVIADGLGLRHVVV
GSDFCFGKGRAGTAEDLKRFGEDMGFGVTIAPLMEYSEDTVSSTAIRRALSDGRPRDAAN
MLGHWHRIEGEVIGGEQRGRELGYPTANMSIDGLHQPAFGVYAVLVDVLDGPHQGSYHGA
ASVGVRPMFDGSHPNIETFLFDFTGNLYGATLSVGLVEYLRPEMTFDGLDGLLAQMDADC
TQARSLLATL