Protein Info for HP15_2363 in Marinobacter adhaerens HP15

Annotation: major facilitator superfamily MFS_1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 73 to 92 (20 residues), see Phobius details amino acids 100 to 114 (15 residues), see Phobius details amino acids 134 to 158 (25 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 219 to 232 (14 residues), see Phobius details amino acids 241 to 264 (24 residues), see Phobius details amino acids 284 to 302 (19 residues), see Phobius details amino acids 309 to 328 (20 residues), see Phobius details amino acids 334 to 360 (27 residues), see Phobius details amino acids 372 to 396 (25 residues), see Phobius details amino acids 402 to 421 (20 residues), see Phobius details PF13000: Acatn" amino acids 4 to 93 (90 residues), 32.7 bits, see alignment E=3.2e-12 PF07690: MFS_1" amino acids 5 to 241 (237 residues), 36.6 bits, see alignment E=2.6e-13 amino acids 247 to 424 (178 residues), 37.9 bits, see alignment E=1.1e-13

Best Hits

KEGG orthology group: K08218, MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG (inferred from 88% identity to maq:Maqu_2584)

Predicted SEED Role

"AmpG permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PH24 at UniProt or InterPro

Protein Sequence (445 amino acids)

>HP15_2363 major facilitator superfamily MFS_1 (Marinobacter adhaerens HP15)
MIALLFLGFSAGLPFLLVFSTLNARLADVGVETATIGFFSWLGITYSIKVFWAPVVDRLK
LPLLDRLLGKRRSWIIFAQAGIATGLYLMAHVDATAAPEMMALCGLLVAFSSATQDVAID
AYRIEIAEERLQAALAATYIFGYRLALLVAGAGALYLAEFWSWQVSYEVMAALVGVGALT
VLIVREPSVNHFAAAQDIAHKIEQEAAKLTHLNPRLARLVGWFYAAVAGPFLDFFRRYKE
LALVILLMVAVYRISDIAMGVMANPFYLDFMGFSKTQVADVTKIFGFFMTIAGSLVGGVM
VVRYGVRRILLLGAIMTAATNLLFVVLAQYPPNIITLAAVVSADNLSGGIANVALIAWLS
SMTSASFTATQYALFSSLMTLPGKFLGGFSGIVVAGFGYAEFFLVAGIMGVPAILLAIFM
IRNGHRLDALAPRNESKPDAEAMSP