Protein Info for Psest_2456 in Pseudomonas stutzeri RCH2

Annotation: Transglutaminase-like enzymes, putative cysteine proteases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 transmembrane" amino acids 12 to 43 (32 residues), see Phobius details amino acids 58 to 74 (17 residues), see Phobius details amino acids 80 to 98 (19 residues), see Phobius details amino acids 106 to 123 (18 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 549 to 570 (22 residues), see Phobius details PF11992: TgpA_N" amino acids 14 to 327 (314 residues), 271 bits, see alignment E=2e-84 PF01841: Transglut_core" amino acids 353 to 468 (116 residues), 88.9 bits, see alignment E=4.2e-29 PF13559: DUF4129" amino acids 584 to 652 (69 residues), 44.6 bits, see alignment E=1.9e-15

Best Hits

Swiss-Prot: 68% identical to TGPA_PSEAE: Protein-glutamine gamma-glutamyltransferase (tgpA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 88% identity to psa:PST_1909)

Predicted SEED Role

"FIG001454: Transglutaminase-like enzymes, putative cysteine proteases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GJS6 at UniProt or InterPro

Protein Sequence (666 amino acids)

>Psest_2456 Transglutaminase-like enzymes, putative cysteine proteases (Pseudomonas stutzeri RCH2)
MSVKPGIPRNSLIWLLVAQVLVILPHLTHLPLWIIGLWLGCAAWRIQIFRMRARYPRSWL
KALLMIGAGFGVYFSRGSLVGLEAGVVLLIAAFILKLVEMSSRRDALVLIFLGFFAVVTS
YLFEDSLLAGLYSLLPVTALLAAMIGLQQSSLVTRPWPTVRLAGSLLLQAVPLMLVLFLF
FPRLPPLWSLPQAGDRGTTGLADHMAPGDIARLGRSPELAFRVSFDGDIPPRDQLYWRAV
TFERFDGRRWSQSYASHLPQEPEWQAVGEPLRYNVVMQPSGQPWLFALDVAQVAPGQAQL
MTDFHLQRRQPVNQPLMYQVTSWLDARREAVRAPESLGRSLQLPERGNSRARAWAMELRR
TAQEPQAMVDALLKHFNRQPYHYTLEPPPVGDDIVDDFLFETRSGFCAHYAGAMTFVLRA
AGIPARVVAGYQGGEVNPAGNYLSVHQFDAHAWVEYWLAERGWVSVDPTFQVAPERVEQG
LEQALARERSFLADQPMSLLRYRDIGWVNALRLRWDSLNYGWQRWVLNYQGEQQTQVLQR
WLGKLDAQALGLGLVAVLALLTAVLALFLFKPWRRETDLQQRLFGRFERLLARHGVHRYK
GEGARSFAERAATMLPGQAPAIRAFVRLYEAQRYAQQPGATDELAHSLRQLRRALPWRLP
KRAGRS