Protein Info for HP15_2313 in Marinobacter adhaerens HP15

Annotation: flagellar biosynthesis protein, FliO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 39 to 62 (24 residues), see Phobius details TIGR03500: flagellar biosynthetic protein FliO" amino acids 48 to 114 (67 residues), 72.8 bits, see alignment E=9e-25 PF04347: FliO" amino acids 60 to 137 (78 residues), 68.6 bits, see alignment E=2.1e-23

Best Hits

KEGG orthology group: K02418, flagellar protein FliO/FliZ (inferred from 77% identity to maq:Maqu_1985)

Predicted SEED Role

"Flagellar biosynthesis protein FliQ" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGG6 at UniProt or InterPro

Protein Sequence (149 amino acids)

>HP15_2313 flagellar biosynthesis protein, FliO (Marinobacter adhaerens HP15)
MWSKSIAVLALLLINPAFAQETAKTVAPDSPVRAPDTVGTIVSLGLGLVAVIAVIYGCAW
IIRRMNGMTGMNNNAIKVVSVMAIGARERIALIEVGGQQILLGITPSAIRTLHVFDEPVV
EAGSAGSSDFARRLQGMIGKSWTSPTRND