Protein Info for Psest_2410 in Pseudomonas stutzeri RCH2

Annotation: Superfamily I DNA and RNA helicases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 656 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00580: UvrD-helicase" amino acids 119 to 456 (338 residues), 114.4 bits, see alignment E=1.6e-36 PF13245: AAA_19" amino acids 127 to 439 (313 residues), 39.3 bits, see alignment E=1.4e-13

Best Hits

KEGG orthology group: None (inferred from 79% identity to psa:PST_1951)

Predicted SEED Role

"UvrD/REP helicase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMB1 at UniProt or InterPro

Protein Sequence (656 amino acids)

>Psest_2410 Superfamily I DNA and RNA helicases (Pseudomonas stutzeri RCH2)
MLSAVKRYRALVAGVLQRCFPRTSAHLREEDELLFRRWGTAPGKANKAATAKRKGKPAAK
AKPKSKSEGPARAAGKPRGTAAQGIYAAAQLKVDDAQVQAMRERVEQAVAAGIISAPSEE
QWAMILSRSPVTRIFAGAGSGKSTTLLLRVVFMLCHMGIEPGRLTVISFTNASCAQLREQ
LVRVLGFWQVPFDAQQARQCVRTFHSAMAQLAREVLERPVWFEQLDDKAAAADEPDNPLA
TARLRPAQVRLLKQAYQQCYAEQATFRELVHRLLDLPAPQTESEQGKRAALKAPGDTFTL
AGEFTPLPLYEAFYAQAGFIESIGIRIDQLQPGKLQCAPRERDFVEALVSFHGYFRAALR
EQGLMTFNEAFQQLTERLASGSDMPQACLVPFENLLIDEFQDISPQIVQWLQALHRQLAR
QKSSPSLMAIGDDWQSIYGWRGSSPELFMDFDKYFPRRGAKGSETLLLETNYRSIEPVIR
DGEAVLAGVQFKQAKTSRPCKPTQPGDHGVKLVTGFELNKGLPKLIEAITAQCAHVAERQ
SRERTAVLLLSRRNEPLRTIQAQLDRKLPVKAYTIHRAKGLQAEVAIIVDDCAPVQPHPL
RNALYAYSGFFRNSYDQAMADESLRLGYVAITRGVSRVFWYTRKAQGATERLARRG