Protein Info for HP15_2293 in Marinobacter adhaerens HP15

Annotation: protein containing CheW-like domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 transmembrane" amino acids 126 to 145 (20 residues), see Phobius details PF01584: CheW" amino acids 124 to 254 (131 residues), 49.8 bits, see alignment E=1.5e-17

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 74% identity to maq:Maqu_1967)

Predicted SEED Role

"CheW domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGE6 at UniProt or InterPro

Protein Sequence (269 amino acids)

>HP15_2293 protein containing CheW-like domain (Marinobacter adhaerens HP15)
MADDKLTRLADPETAIASYLDELLHTATDTALREEIEAPEPVKPAPPEPRVATRTKPASV
PTVEKPAARPEPPKRVRETPAEPERPVVRQAPEAPVPKARIETQPAPEPAAPPSRPEWSE
QPFECLIFTVAGLQLAVPLILLGAIHRIEEEIRPIPGSPRWYMGIRPDRDQNLRVVDTAE
WIMAGRVPPDARDNYRFVIRLDNSDWGLACDDVAQSFTLRPDEVRWRTARSKRPWLAGTV
IDHMCALIDVRTMADLLVRAEREHHLDLS