Protein Info for PGA1_c23490 in Phaeobacter inhibens DSM 17395

Annotation: NADH:flavin oxidoreductase/NADH oxidase, containing FAD binding domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 764 PF00724: Oxidored_FMN" amino acids 397 to 727 (331 residues), 221.6 bits, see alignment E=1.8e-69

Best Hits

KEGG orthology group: K09461, anthraniloyl-CoA monooxygenase [EC: 1.14.13.40] (inferred from 83% identity to sil:SPOA0407)

MetaCyc: 56% identical to 2-aminobenzoyl-CoA monooxygenase/reductase subunit (Aromatoleum evansii)
Anthraniloyl-CoA monooxygenase. [EC: 1.14.13.40]

Predicted SEED Role

"Anthraniloyl-CoA monooxygenase (EC 1.14.13.40)" (EC 1.14.13.40)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EP18 at UniProt or InterPro

Protein Sequence (764 amino acids)

>PGA1_c23490 NADH:flavin oxidoreductase/NADH oxidase, containing FAD binding domain (Phaeobacter inhibens DSM 17395)
MKIACLGGGPAGLYFAISTKLRQPDAEITVFERNKPDDTFGWGVVLSDDALENLTTNDPV
SAGQIRDKFAYWDDIAVVHGGVRTVSGGHGFAGIGRKAMLVILQERARELGVDLQFETEV
GPAASYQAEYDLVVACDGLNSRVRSEFAEHFKPNVDVRPCKFIWLGTKQKFDDAFTFIFE
KTQHGWLWIHAYQFDADTATVIVECFAQTWENWGFEAMSKDEILRTCEEIFANHLGGHAL
ISNADHLRGSAVWINFPRVLCETWHHENVVLLGDASATAHFSIGSGTRLAFDSAIALAEF
ITTEPTLEQAFVRYQEERRLDVLRLQSAARNSLEWFEEVERYLDMDPVQFNYSLLTRSQR
ISHENLRLRDADWLASAEKWFQETAGAPADAPTRAPMFAPYKLREMQLKNRIVVSPMAQY
KAKDGCPTDWHLIHYGERAKGGAGLVYTEMTCVSAEGRITPGCPGLYAPEHEAAWARLTG
FVHAETDAKICCQIGHSGRKGSTQLGWETMDAPLRDGNWETVSASAIAWSDGNAPPREIT
RAEMDAIKGEFVAAAQMAERAGFDMIELHAAHGYLISSFISPKSNIRTDAYGGSLENRLR
YPLEVFDAMRAVWPADKPMSVRISANDWVGDEGVTPEEAVEIARAFTAAGADIIDVSAGQ
TSTEAQPVYGRMFQTPFSDRIRNDAGIATMAVGNIYEADHANSILMAGRADLVCVGRPHL
ADPYWTLHEASRIGDRHADWPLPYLAGRDQAWRLADRDAEVIRA