Protein Info for PGA1_c23220 in Phaeobacter inhibens DSM 17395

Annotation: protein HipA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 TIGR03071: HipA N-terminal domain" amino acids 10 to 110 (101 residues), 87.8 bits, see alignment E=2.3e-29 PF13657: Couple_hipA" amino acids 11 to 109 (99 residues), 85.6 bits, see alignment E=2.9e-28 PF07804: HipA_C" amino acids 152 to 393 (242 residues), 177.5 bits, see alignment E=3.2e-56

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 54% identity to aeh:Mlg_2301)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DSG3 at UniProt or InterPro

Protein Sequence (430 amino acids)

>PGA1_c23220 protein HipA (Phaeobacter inhibens DSM 17395)
MAKHGRSGTMQVLLNGRSVGALRLAGSGAISFTYDPEWLAWVHAMPISQSLPLREEAHQG
GPVIAYLENLLPDNQAIRERVAARVRAGGTDAWHMLEKIGRDCVGALQFVSGEIPEFAVL
EGEPVSEAQIADMLRNLASAPLGLDEEDDFRISIAGAQEKTALLRHEGAWIRPSGLTPTT
HIFKTQLGVLPAGIDLSDSVENEFFCMSFCRAMGLDVAEVEITDFEDVRSLVVTRFDRRW
TKDGRLIRLPQEDFCQALSVPPSQKYQMDGGPGITEGIGLLTGSDDPEADQRVFFRAQVL
FWLLGATDGHAKNFSIALRPGGFRMTPLYDVLSAQKAVDDGQIRQNRMRLAMAVDGHYRI
NEVVPRHFLQAAKVAGFGVALAEEVLSGVATELEPALDKTLADLPDGFPQLLAEAIVAGI
RRRAAAFHAV