Protein Info for PGA1_c23120 in Phaeobacter inhibens DSM 17395

Annotation: putative sorbitol dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF00106: adh_short" amino acids 9 to 207 (199 residues), 151.4 bits, see alignment E=3.5e-48 PF08659: KR" amino acids 11 to 123 (113 residues), 25.9 bits, see alignment E=1.3e-09 PF13561: adh_short_C2" amino acids 15 to 266 (252 residues), 151.4 bits, see alignment E=5e-48

Best Hits

KEGG orthology group: None (inferred from 61% identity to pin:Ping_2778)

Predicted SEED Role

"Sorbitol dehydrogenase (EC 1.1.1.14)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization (EC 1.1.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.14

Use Curated BLAST to search for 1.1.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DSF2 at UniProt or InterPro

Protein Sequence (269 amino acids)

>PGA1_c23120 putative sorbitol dehydrogenase (Phaeobacter inhibens DSM 17395)
MDPNRLKGKNILITGAARGMGQANAESFAAQGANVCLGDLDGDEAQKVADAINAAGNGMA
IAVKMDVTSRADNAAAVAATVEAFGSINVGLFNAGLNKPRFFMDIDEDNWDMIMNVNTKA
MWLGMQEVARQMIAQGPMEDHPYKLINVGSIASKKPLVDVTVYCTSKYGCLALTECGALG
LAEHNITVNGYAPGVVVTPLWEQLDKDLVDIGFKEREGQAYEDIVDSALVIKRLSYPKDI
VGTASFLASDDSDYMTGQMISIDGGWATT