Protein Info for HP15_2195 in Marinobacter adhaerens HP15

Annotation: amino acid ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 transmembrane" amino acids 24 to 42 (19 residues), see Phobius details amino acids 54 to 74 (21 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 126 to 148 (23 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 257 to 279 (23 residues), see Phobius details amino acids 306 to 321 (16 residues), see Phobius details amino acids 364 to 386 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 85 to 149 (65 residues), 60.6 bits, see alignment E=8.6e-21 PF00528: BPD_transp_1" amino acids 224 to 390 (167 residues), 51.2 bits, see alignment E=6.6e-18

Best Hits

Swiss-Prot: 57% identical to YHDX_ECOLI: Putative amino-acid ABC transporter permease protein YhdX (yhdX) from Escherichia coli (strain K12)

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 63% identity to rru:Rru_A1003)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PF79 at UniProt or InterPro

Protein Sequence (395 amino acids)

>HP15_2195 amino acid ABC transporter, permease protein (Marinobacter adhaerens HP15)
MKKQTIDTRPAGPKPWYDPRVRSLFFQAVAIALVFWGGWILVDNTLSNMESRGISTGFGF
LGETAGFGIIMNLVPYDATMSYGRTFWVGLTNTLLVSAMGVVAATILGFIIGVARLSSNW
LVAKMALVYIEVIRNIPLLLQIFFWYFAVLSNLPSPRQSVDVGGALFLNNRGLYLPDPVT
QEGFGIVWGGILLAIAAVVGIRIWAKKRQLATGQIFPTFKVGVAILVLVPIISYLVAGRP
LEWDLPALRGFNFGGGITIIPELAALWIALSLYTASFIAEIVRSGILSVSKGQTEASKAL
GLPNGLTLRLVVIPQAMRVIIPPLTSQYLNLVKNSSLATAIGYPDLVAVFMGTTLNQTGQ
AVEVVAITMAVYLTISLLISLFMNIYNRAVAIKER