Protein Info for Psest_2262 in Pseudomonas stutzeri RCH2

Annotation: Co/Zn/Cd efflux system component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 transmembrane" amino acids 120 to 139 (20 residues), see Phobius details amino acids 151 to 168 (18 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 206 to 227 (22 residues), see Phobius details amino acids 248 to 265 (18 residues), see Phobius details amino acids 271 to 289 (19 residues), see Phobius details PF00403: HMA" amino acids 32 to 82 (51 residues), 25.3 bits, see alignment 1.6e-09 PF01545: Cation_efflux" amino acids 119 to 289 (171 residues), 51.2 bits, see alignment E=1.4e-17

Best Hits

KEGG orthology group: None (inferred from 60% identity to maq:Maqu_1408)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcD" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GLA9 at UniProt or InterPro

Protein Sequence (293 amino acids)

>Psest_2262 Co/Zn/Cd efflux system component (Pseudomonas stutzeri RCH2)
MSCADQDCGCGSAAASNPAGELESGAARWISVYRVPKMDCPAEERMIRMALASCEGIRHL
AFDLPNRTLTVAHDCSVDPLSERLEALGLGAGLTRTHAAEGAPDVLAGDTQEQEAATLKI
LLAINAIMFIFELVAGLVAQSTGLIGDSLDMFADAAVYGVALYAVGRAARFQLRAAQLAG
WLQGLLALGLLVEVGRRFFFGSEPQSLTIMVVACVALIANVACLLLITKHRDGGVHMQAS
YIFSANDVLINVGVIVAGALVAWSGSNYPDLFIGGLIGLIVLLGARRILALRA