Protein Info for PGA1_c22190 in Phaeobacter inhibens DSM 17395

Annotation: lipid A export ATP-binding/permease protein MsbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 599 transmembrane" amino acids 35 to 57 (23 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 177 to 195 (19 residues), see Phobius details amino acids 258 to 280 (23 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details TIGR02204: ABC transporter, permease/ATP-binding protein" amino acids 19 to 592 (574 residues), 882.7 bits, see alignment E=6.3e-270 PF00664: ABC_membrane" amino acids 38 to 306 (269 residues), 146 bits, see alignment E=1.8e-46 PF00005: ABC_tran" amino acids 374 to 521 (148 residues), 118.2 bits, see alignment E=4.2e-38

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 82% identity to sit:TM1040_1828)

Predicted SEED Role

"ABC transporter, ATP binding/permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F0V2 at UniProt or InterPro

Protein Sequence (599 amino acids)

>PGA1_c22190 lipid A export ATP-binding/permease protein MsbA (Phaeobacter inhibens DSM 17395)
MAGNQAVPTADVEREKSRKVGVLSALWPFMRPYRVLMAMATLALVLTAGLSLTLPLAVRR
VVDNFRISEAALLNQYFAAALVIAALLAVGTGLRYALVTRLGERVVADIRKAVFDRVIGM
SPAFFEQIMTGEVLSRITTDTTLIQSVLGSSVSIALRNMLIFIGGLVLMLLTSAKLTSLV
LLIVPAVIVPILVLGRRLRKISRENQDWIAASSGNAGEALGAVQTVQAYTHEVASRSEFS
RLTETAFDVSMRRIQTRAFLTVIVIFLVFSGVVGVLWMGANDVRAGIMSEGTLVQFVIYA
VLVAGSVAALSEIWSELQRAAGATERLVELLTAVDQVQDPYAPRALAAPVRGEIRFDDVS
FRYPARPQIPALVDVSLTVQPGETVAFVGPSGAGKTTIIQMIQRFYDPTSGAVCLDGRPL
RDLQRDDFRQHIALVPQDPVIFALSARDNIRFGRPGASDAEVEAAARAAAAHDFISALPE
GYDSQVGERGVMLSGGQKQRIAIARAILRDAPVLLLDEATSALDAESERLVQAAVDELSQ
GRTTLIVAHRLATVKKADRIVVMEEGRIIATGTHDQLVAEDGLYARLARLQFTDGMAAE