Protein Info for PGA1_c21740 in Phaeobacter inhibens DSM 17395

Annotation: transcriptional regulator, ArgP family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR03298: transcriptional regulator, ArgP family" amino acids 3 to 291 (289 residues), 364.4 bits, see alignment E=1.9e-113 PF00126: HTH_1" amino acids 6 to 62 (57 residues), 55.4 bits, see alignment E=4.9e-19 PF03466: LysR_substrate" amino acids 91 to 285 (195 residues), 53.7 bits, see alignment E=1.9e-18

Best Hits

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 68% identity to sil:SPO1078)

Predicted SEED Role

"Chromosome initiation inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F0S1 at UniProt or InterPro

Protein Sequence (294 amino acids)

>PGA1_c21740 transcriptional regulator, ArgP family (Phaeobacter inhibens DSM 17395)
MKFDPNHLAALSAVLRLGSFEAAAQALLVTPSAISQRIKALEDRIGSSLVQRGSPCLGTE
AGLRIAKHAEDVALLEAAVSEDLRLERAPGASRLRVAINADSLATWFVPVMAACDGLLFD
LVIDDQDHSADWLRRGEVSAAVTAHAKPVTGCDAHPLGALRYIATASPRFRERWFANGVT
QEAATRAPCLIFNAKDQLQARWLGAHVGQGVAPPAHFLPSSQAFVDAALAGVGWGMNPEQ
LAAPYLAAEQLCPLIPNTPLDVPLTWQVSRVLAPALADVTRAVLKSARRHLTPI