Protein Info for HP15_2087 in Marinobacter adhaerens HP15

Annotation: protein belonging to uncharacterized protein family UPF0274

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF04356: DUF489" amino acids 7 to 198 (192 residues), 265 bits, see alignment E=2.3e-83

Best Hits

Swiss-Prot: 78% identical to HFLD_MARHV: High frequency lysogenization protein HflD homolog (hflD) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K07153, high frequency lysogenization protein (inferred from 78% identity to maq:Maqu_1763)

Predicted SEED Role

"FIG002903: a protein of unknown function perhaps involved in purine metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRE2 at UniProt or InterPro

Protein Sequence (214 amino acids)

>HP15_2087 protein belonging to uncharacterized protein family UPF0274 (Marinobacter adhaerens HP15)
MSRSLKDQTLALAGVFQAANLVQQIAHNGQCNEASLETSIRSLFATNPENTLDVYGGELR
DIREGLVTLSSVLSQQSRQQDIEVLRYALNLIQLESKLNRRSDMLDVIGSRIDQARHTAS
HFGYTHPNLISNLASVYADTISTFRQRIQVSGNPSVLQREENAAKVRALLLAGIRSAVLW
RQTGGRRWQLIFARKKVIGLAKELAEEANRSLYH