Protein Info for PGA1_c20970 in Phaeobacter inhibens DSM 17395

Annotation: alpha/beta hydrolase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 PF12146: Hydrolase_4" amino acids 30 to 135 (106 residues), 32.7 bits, see alignment E=7.3e-12 PF12697: Abhydrolase_6" amino acids 52 to 231 (180 residues), 36.1 bits, see alignment E=1.7e-12 PF00561: Abhydrolase_1" amino acids 56 to 143 (88 residues), 39.3 bits, see alignment E=9.2e-14

Best Hits

KEGG orthology group: None (inferred from 74% identity to sit:TM1040_1720)

Predicted SEED Role

"2-hydroxymuconic semialdehyde hydrolase (EC 3.1.1.-)" (EC 3.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.-

Use Curated BLAST to search for 3.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EY47 at UniProt or InterPro

Protein Sequence (259 amino acids)

>PGA1_c20970 alpha/beta hydrolase domain-containing protein (Phaeobacter inhibens DSM 17395)
MAATQFLDTDTGRRLAYHLTPASSDATAPTVVFLGGLKSDMQGTKAVHLEAWAKARGLGF
LRFDYSGHGESSGTFEEGCIGDWHQDTLAAVQALTKGQILPVGSSMGGWQALLLARTLPE
RVAGLVTIAAAPDFTEDGYWANFTDTQKAELETRGQVELPSDYMEPYVITKRMIEDGRNH
LVLRDPLVLSMPVRCLQGTADTAVSTETALRLLDHATCADMRLQLVKDADHRFSDPACLA
LIETAVAEVLGLSGADAIS