Protein Info for PGA1_c20870 in Phaeobacter inhibens DSM 17395

Annotation: molybdenum hydroxylase family protein, large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 787 PF01315: Ald_Xan_dh_C" amino acids 21 to 139 (119 residues), 95.2 bits, see alignment E=4.7e-31 PF02738: MoCoBD_1" amino acids 155 to 406 (252 residues), 254.7 bits, see alignment E=1.1e-79 PF20256: MoCoBD_2" amino acids 434 to 720 (287 residues), 306.5 bits, see alignment E=3.2e-95

Best Hits

KEGG orthology group: None (inferred from 92% identity to sit:TM1040_1765)

Predicted SEED Role

"Carbon monoxide dehydrogenase large chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EY40 at UniProt or InterPro

Protein Sequence (787 amino acids)

>PGA1_c20870 molybdenum hydroxylase family protein, large subunit (Phaeobacter inhibens DSM 17395)
MPKDSGIGASPKRREDVRFLTGTGNYTDDINMRGQAYVHFLRSDVAHGRLTSVDTSDAAA
MPGVVRIFTGADFEGVGGLPCGWQVTDRHGEVMQEPAHPVLAQGKVRHVGDPIAAVVAET
PEQARDAAEAIVLDIEDLPAVINMKEAVKDGATKVHDDLTSNLCYDWGFVEENRGAVDKA
IKDAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGDSTLYTTSQNPHVIRLLMGAFVLG
IPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDAHGRDH
VTKIELALDADNNFTALRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIYVNVKA
VFTNTVAVDAYRGAGRPEATYQLERVIDKAARELGVDPIALRRQNFITEFPYATPVAVEY
DTGDYVATMDKLEEIADLSGFDARRAASKAKGKLRGLGVNCYIEACGIAPSNLVGQLGAR
AGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIADMIGIPEDMVEIEHGDTDKAP
MGMGTYGSRSLAVGGSAMVRATEKIIAKAKKIAAHILEASDADIELKDGQFTVAGTDKSL
AWGDVTLAAYVPHNYPLEDIEPGLEETAFYDPANFTYPSGAYACEVEVDPDTGKVTIERF
AAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDDDGQLLSASFMDYAMPRADDLP
FYKVDHSCQTPCTHNPLGVKGCGEAGAIGTPPAVVNAVVDALQSAGKDVTHIDMPLSPAR
VWAAMNG