Protein Info for Psest_2033 in Pseudomonas stutzeri RCH2

Annotation: periplasmic chaperone LolA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR00547: outer membrane lipoprotein carrier protein LolA" amino acids 2 to 205 (204 residues), 105.1 bits, see alignment E=1.8e-34 PF03548: LolA" amino acids 36 to 197 (162 residues), 197.3 bits, see alignment E=1.5e-62

Best Hits

Swiss-Prot: 76% identical to LOLA_AZOVD: Outer-membrane lipoprotein carrier protein (lolA) from Azotobacter vinelandii (strain DJ / ATCC BAA-1303)

KEGG orthology group: K03634, outer membrane lipoprotein carrier protein (inferred from 98% identity to psa:PST_2292)

Predicted SEED Role

"Outer membrane lipoprotein carrier protein LolA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GLB0 at UniProt or InterPro

Protein Sequence (208 amino acids)

>Psest_2033 periplasmic chaperone LolA (Pseudomonas stutzeri RCH2)
MQLIRLLCASVLMVALAPAHADQAASTKRLTGLLNQAETLTGRFSQLSLDGSGTQLQETS
GELALKRPGQFRWHTDAPMEQLLVSNGKKVWLYDPDLEQVTIQELDQRLTHTPALLLSGD
VSTISENFEVSHKEAGEVVDFTLKPKAKDTLFDNLRLSFRNGVINDMQLIDSVGQRTNIL
FMGVQMNQPLKADLFTFEIPEGADVISE