Protein Info for HP15_1938 in Marinobacter adhaerens HP15

Annotation: conserved hypothetical protein, membrane

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 127 to 147 (21 residues), see Phobius details amino acids 158 to 183 (26 residues), see Phobius details amino acids 203 to 227 (25 residues), see Phobius details amino acids 235 to 260 (26 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details PF03706: LPG_synthase_TM" amino acids 14 to 296 (283 residues), 128.5 bits, see alignment E=1.9e-41

Best Hits

Predicted SEED Role

"dolichol-P-glucose synthetase homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQ22 at UniProt or InterPro

Protein Sequence (307 amino acids)

>HP15_1938 conserved hypothetical protein, membrane (Marinobacter adhaerens HP15)
MTELRQRQVRLAARWLFTVLVIGFVIRSIDSGELWQELARFSPYVLVPALALTVFQVALS
AWRWRYTVERLGLPLAYGVAVREYYLATFLNQVLPGGVLGDVNRAWRHGSGAGERLSAVH
GVAIERLSGQLVLALVVVISGIWLLGSGRVAAGQWNGGLLLGAGVIGVFLALWLALKTGL
AAYLQRLRRDLYESLLNRTVLPVQIGSSLLVLASYLGVFLCLAWGAGYIESTESAAIIVS
LGSILLLSMVVPLTVAGWGIREGAAALLWPMAGLPAEQGVALSVGYGALVLVSSLPGAAF
FRPTHHG