Protein Info for Psest_2000 in Pseudomonas stutzeri RCH2

Annotation: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00106: adh_short" amino acids 15 to 210 (196 residues), 158.5 bits, see alignment E=2.3e-50 PF08659: KR" amino acids 16 to 182 (167 residues), 40.5 bits, see alignment E=4.2e-14 PF13561: adh_short_C2" amino acids 20 to 243 (224 residues), 121.5 bits, see alignment E=6.6e-39

Best Hits

Swiss-Prot: 51% identical to YCIK_ECOLI: Uncharacterized oxidoreductase YciK (yciK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to psa:PST_2325)

MetaCyc: 54% identical to CAI-1 synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
1.1.1.-

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMI8 at UniProt or InterPro

Protein Sequence (246 amino acids)

>Psest_2000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) (Pseudomonas stutzeri RCH2)
MFEYSARPDLLKGRIILVTGAGRGIGEAAAKAYAAHGATVLLLGKNEDNLNRVYDDIEAA
GHPHPAIIPFNLETALPHQYDELAAMIEREFGHLDGLLHNAAIVGPRTPLEQLSGDNFMR
VMQVNVNAMFMLTSTLLPLLKLAKDASVIFTSSSVGRKGRAYWGAYAVSKFATEGLMQVL
ADEVDETAPVRANSINPGATRTDMRAKAYPGENPQVNPLPEEIMPVYLYLMGPDSIGVNG
QALNAQ