Protein Info for PGA1_c19890 in Phaeobacter inhibens DSM 17395

Annotation: peptide chain release factor 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 351 TIGR00019: peptide chain release factor 1" amino acids 6 to 349 (344 residues), 482.6 bits, see alignment E=3.3e-149 PF03462: PCRF" amino acids 12 to 198 (187 residues), 228.9 bits, see alignment E=4.9e-72 PF00472: RF-1" amino acids 206 to 314 (109 residues), 135.9 bits, see alignment E=6.4e-44

Best Hits

Swiss-Prot: 83% identical to RF1_RUEPO: Peptide chain release factor 1 (prfA) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

KEGG orthology group: K02835, peptide chain release factor 1 (inferred from 83% identity to sil:SPO2461)

Predicted SEED Role

"Peptide chain release factor 1" in subsystem LMPTP YwlE cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E1Q7 at UniProt or InterPro

Protein Sequence (351 amino acids)

>PGA1_c19890 peptide chain release factor 1 (Phaeobacter inhibens DSM 17395)
MIPEDRLEQILQRFQYLEAAMAEGVAGADIAALAKEYSDLRPVAEQITAYRRLLCDLEEA
EQMLADPDMAELAEEELPQLRAALPEAEHALQLALLPRDEADARPAMLEIRPGTGGDEAA
LFAGDLLRMYQRYAEARGWGFEIIEEQTTELGGLKEVVAHVKGENVFARLKYESGVHRVQ
RVPVTESGGRIHTSAATVAVLPEAEDVDLRIDPGDLRIDTMRASGAGGQHVNTTDSAVRI
THIPTGIIVVSSEKSQHRNREIAMQVMRTRLYDLERQRIDSERSADRASQVGSGDRSERI
RTYNFPQGRMSDHRINLTLYKLDQIMQGDLDEIIDALTADDQARLLAEMGQ