Protein Info for Psest_1924 in Pseudomonas stutzeri RCH2

Updated annotation (from data): adhesin-associated MmpL efflux pump
Rationale: Conserved cofit with a putative adhesin (Psest_1122). The MmpL family is involved in efflux of lipids or siderophores (see IPR004869); we speculate that this exports a lipid or saccharide that is attached to the adhesin.
Original annotation: Predicted exporters of the RND superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 784 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 236 to 257 (22 residues), see Phobius details amino acids 264 to 285 (22 residues), see Phobius details amino acids 292 to 309 (18 residues), see Phobius details amino acids 336 to 359 (24 residues), see Phobius details amino acids 368 to 392 (25 residues), see Phobius details amino acids 423 to 442 (20 residues), see Phobius details amino acids 623 to 641 (19 residues), see Phobius details amino acids 648 to 669 (22 residues), see Phobius details amino acids 675 to 696 (22 residues), see Phobius details amino acids 722 to 742 (21 residues), see Phobius details amino acids 752 to 775 (24 residues), see Phobius details PF03176: MMPL" amino acids 476 to 773 (298 residues), 85.4 bits, see alignment E=1.9e-28

Best Hits

KEGG orthology group: K07003, (no description) (inferred from 98% identity to psa:PST_2413)

Predicted SEED Role

"FIG005548: transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMD1 at UniProt or InterPro

Protein Sequence (784 amino acids)

>Psest_1924 adhesin-associated MmpL efflux pump (Pseudomonas stutzeri RCH2)
MTKHQQKPASFLERLIFNNRPAVVVLCLLISAFLFYQAAQVRPQTSFEKMIPLAHPYIQK
MLEHQNDLANLGNTVRISVEAVEGDIFSKEYMETLRQIHDEVFYIHGVDRSNMKSLWSPS
VRWTEVTEEGFAGGEVIPQTYDGSPESLDDLRDNILKSGQIGRLVANNFKSSIIDVPLLE
SYPDPEDQSRQIKLDYQKFSHELEEKIREKYQAQNPNVKVHIIGFAKKVGDLIDGLVGVA
LFFIVAIGITFVLLLWFTRCLKSTIAVLITTLIAVTWQLGLLHTLGFGLDPYSMLVPFLV
FAIGISHGVQKINGIAMASGYTEDPVTAARMAFRQLFIPGMVALLSDAVGFVTLLLIDIG
VIRELAIGASLGVAVIILTNLILLPVAISYMGISQRAIKQAREEASRDHPFWRALSNFAS
PKVAPISITIAVVALAGGLWYGQNLKIGDLDQGAPELHPDSRYNLDNDFVIRNYSTSSDV
LVVMVKTAPEGCSHYDTLAAMDELMWKMQNTEGVQSAVSMVSVARQGIKGMNEGSLKWET
LSRNPHVLNNSIARAEGMYNSDCSLAPVLVFLNDHKAETLEHVVAAAKDFAEENNREGLE
FVLAAGNAGIEAATNEVIAASETTMLIAVYLAVSIMCLLTFRSLAATLCVILPLVLTSIL
GNALMAFMGVGVKVATLPVIALGVGIGVDYGIYIYSRLESFLRQGMTLQEAYYQTLKSTG
KAVIFTGVCLAIGVVTWVFSAIKFQADMGMMLTFMFLWNMVGAIWLLPALARFLIKPEKL
RQKA