Protein Info for Psest_1825 in Pseudomonas stutzeri RCH2
Annotation: Predicted nucleoside-diphosphate sugar epimerases
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 76% identity to pae:PA3141)MetaCyc: 76% identical to UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (Pseudomonas aeruginosa)
RXN-13252 [EC: 4.2.1.135]
Predicted SEED Role
"nucleotide sugar epimerase/dehydratase WbpM"
MetaCyc Pathways
- UDP-2-acetamido-4-amino-2,4,6-trideoxy-α-D-galactose biosynthesis (2/2 steps found)
- UDP-N-acetyl-α-D-quinovosamine biosynthesis (2/2 steps found)
- UDP-yelosamine biosynthesis (2/3 steps found)
- UDP-N-acetyl-α-D-fucosamine biosynthesis (1/2 steps found)
- UDP-N,N'-diacetylbacillosamine biosynthesis (1/3 steps found)
- superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (9/24 steps found)
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.2.1.135
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0GK49 at UniProt or InterPro
Protein Sequence (671 amino acids)
>Psest_1825 Predicted nucleoside-diphosphate sugar epimerases (Pseudomonas stutzeri RCH2) MFVLSLAEKLRARLVSLPRRYKRLIQLAADIVLVWVALWLAFVVRLGDSKNIEPLDGHAW LFGIAPVIAIPFFIRFGMYRAVMRYFGNDALMAIAKAVTLSALLLSLAVYWNSDAPKLIP RSMVFNYWWLSLVLIGGLRLVMRQYFMGDWFSPTTLTKFKGKEAGLPKVAVYGAGAAGNQ LVAALRMGRAMRPVAFIDDDPNLHNRVIAGLRVYSAKHIGQLVEDTGAGEILLAIPSASR GRRREILEMLERFPLHVRSVPGFMDLASGKVQVEDIQEVDIADLLGRDAVPPQQALFEKC IRGKVVMVTGAGGSIGSELCRQILSNKPQALLLFEHSEFNLYSIHMELERLIERTSLPIR LVPILGSIRNADRLLDVMRTWGVETIYHAAAYKHVPMVEHNVAEGVLNNVIGTLNTAQAA VQAGVSNFVLISTDKAVRPTNVMGSTKRVAELVLQALSREPAPGLFGTAGSVHHVNKTRF TMVRFGNVLGSSGSVIPRFYAQIRAGGPVTVTHPKITRYFMTIPEAAQLVIQAGSMGQGG DVFVLDMGQPVKIAELAEKLIHLSGLSVRSEKCPHGDIAIEYTGLRPGEKLYEELLIGDN VSPTEHPMIMRADEEYLDWDVLKDRLAKLLKAVESDDYPQVRQLLREVVSGYVPEGEIVD WIYQQRRVEPE