Protein Info for PGA1_c17370 in Phaeobacter inhibens DSM 17395

Annotation: uvrABC system protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 966 TIGR00630: excinuclease ABC subunit A" amino acids 7 to 943 (937 residues), 1441.6 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 133 to 239 (107 residues), 128.5 bits, see alignment E=2e-41 PF17755: UvrA_DNA-bind" amino acids 300 to 409 (110 residues), 134.6 bits, see alignment E=3.6e-43

Best Hits

Swiss-Prot: 69% identical to UVRA_BRUSU: UvrABC system protein A (uvrA) from Brucella suis biovar 1 (strain 1330)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EX92 at UniProt or InterPro

Protein Sequence (966 amino acids)

>PGA1_c17370 uvrABC system protein A (Phaeobacter inhibens DSM 17395)
MAELKSIEVRGAREHNLKNIDVDIPRDQLVVITGLSGSGKSSLAFDTIYAEGQRRYVESL
SAYARQFLDMMEKPDVDHISGLSPAISIEQKTTSKNPRSTVGTVTEIYDYLRLLFARAGT
PYSPATGMPIEAQQVQDMVDRIMTLEEGTRGFLLAPIVRDRKGEYRKEFLELRKQGFQRV
KVDGEFYELDEPPTLDKKFRHDIDVVVDRLVVREGVETRLADSLRTALDLADGIAILETA
PRAAEGEEAPEPERITFSENFACPVSGFTIPEIEPRLFSFNAPFGACPECDGLGVELFFD
ERLVVPDQNLKIYDGALAPWRKGKSPYFLQTIEAIAKHYQFNKNTKWKDLPNKVQQVFLR
GSGDEEIKFRYDEGGRVYEVERVFEGVIPNMERRYRETDSNWIREEFERYQNNRSCGVCE
GYRLREEALAVKIGPTGGRPDQLLHVGQVVQMSIREALAWIEDVPNQLSPQKQEIARAIV
KEIRERLGFLNNVGLEYLTLSRNAGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLH
QRDNDRLLETLKNLRDQGNTVIVVEHDEDAIREADYVFDIGPGAGVHGGQVVSHGTPEMV
AADEGSITGQYLSGTREIAVPSVRRKGNGKSVKVVKATGNNLKNVTAEFPLGKFLCVSGV
SGGGKSTLTIETLFKTASMRLNGARQTPAPCETIKGLEHLDKVIDIDQRPIGRTPRSNPA
TYTGAFTPIREWFAGLPESKTRGYKPGRFSFNVKGGRCEACQGDGVIKIEMHFLPDVYVE
CETCKGARYNRETLEIQFKGKSIADVLDMTVEDAQQFFQAVPSIRDKMDALMRVGLGYIK
VGQQATTLSGGEAQRVKLSKELAKRSTGRTLYILDEPTTGLHFEDVRKLLEVLHELVEQG
NSVVVIEHNLDVIKTADWIIDIGPEGGDGGGEIVAAGTPEDVAAAKGSHTGHYLKEILDA
RSLAAE