Protein Info for HP15_1622 in Marinobacter adhaerens HP15

Annotation: NADH dehydrogenase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 45 to 67 (23 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 122 to 139 (18 residues), see Phobius details amino acids 145 to 164 (20 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 216 to 236 (21 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 319 to 342 (24 residues), see Phobius details amino acids 348 to 365 (18 residues), see Phobius details amino acids 375 to 395 (21 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details amino acids 429 to 451 (23 residues), see Phobius details amino acids 458 to 483 (26 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 83 to 123 (41 residues), 33.6 bits, see alignment 2.9e-12 PF00361: Proton_antipo_M" amino acids 142 to 359 (218 residues), 128.9 bits, see alignment E=2.4e-41

Best Hits

Predicted SEED Role

"NADH dehydrogenase, subunit 5" in subsystem Respiratory Complex I

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PM58 at UniProt or InterPro

Protein Sequence (539 amino acids)

>HP15_1622 NADH dehydrogenase subunit L (Marinobacter adhaerens HP15)
MNPIAEFSLLSILALWLLLPVGLFLLAGLTGWLKNPLKVNHCWRLAGWALLASMAVSVVM
GILLLIQPYTGGDSNRLATLGGRFGLYPDGIAVWMATMVAFIGWVILRFADNYLSQDPGR
DRFLPWFLVTVASVLVLVFTNHLLILAGAWIGVSLALHHLLTLYQDRPQARMAAVQKFIV
SRVGDALVVSGVVALYLHYGTFYLPDMVQNEGARAGGSTALTVASVVLALAAVLKCAQIP
FHGWLIRVMEAPTPVSALLHAGVINLGGFLWLRLFPVFDGFTAGHMILLVIGGMTAVVAV
LTMITQYSVKHALAWSTCAQMGFMLFEIGMGAYTLALLHLLAHSLYKAHSFLASGRTVAV
SAATRFPESPSANRLSWAGLTGLLAAAILVQFPWIVENNPVFGALLVLAVSAAAMGIPAG
ATKAVKLKLAGLAVLLVPLYSLLHFLIGPAVPEQEGFAIPGIALGTGATLVTLLAVCSLM
IAFGARFPATRALGVHFRQGLYLELPFDRLTCFLAAEALKVPAMFRRVPHHPFRLEERS